The purpose of this research was to investigate the guidelines for enhancing English proficiency among individuals in the business sector. A mixed-methodology approach, which involved both quantitative and qualitative research methods, was employed. The quantitative data were collected by distributing a questionnaire to 500 Large, Small, and medium enterprises in the manufacturing sector. The data was then analysed using various statistical tests, such as descriptive analysis, inferential analysis, and multivariate analysis. This study identified four crucial elements of the guidelines for enhancing English proficiency among personnel. The key items within each aspect were as follows: 1) Skill Development (x̅ = 4.04): Clearly define career paths based on knowledge and English proficiency to provide growth opportunities for all personnel. 2) Organization Support (x̅ = 4.01): Provide necessary communication equipment to support personnel in developing English competency. 3) Policy and Regulations (x̅ = 4.00): Encourage individuals and teams within the organization to collaboratively develop skills. 4) Collaboration (x̅ = 3.97): Develop knowledge and gain practical experience through a range of collaborative activities. In addition, the hypothesis test revealed significant variations in the overall aspects depending on the size of the manufacturing enterprises, with a significance level of 0.05. The structural equation model analysis demonstrated a strong alignment with the empirical data, meeting the evaluation criteria with a Chi-square probability level of 0.167, a relative Chi-square of 1.073, a goodness of fit index of 0.950, and a root mean square error of approximation of 0.012.